5H-Dibenzo(a,d)cyclohepten-5-ol, 10,11-dihydro-5-(3-dimethylaminopropyl)- - Names and Identifiers
Name | 5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo(a,d)cyclohepten-5-ol
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Synonyms | BRN 2148173 AMitriptyline IMpurity B AMitriptyline Related CoMpound B, USP AMitriptyline Hydrochloride IMpurity D 5-(3-Dimethylaminopropyl)5-dibenzo(a,d)cycloheptadienol 5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo(a,d)cyclohepten-5-ol 5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol 5-(3-Dimethylaminopropyl)-10,11-dihydrodibenzo(a,d)cyclohepten-5-ol 5-(3-Dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepteen-5-ol 5-(3-DIMETHYLAMINOPROPYL)-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-OL 10,11-Dihydro-5-(3-dimethylaminopropyl)-5H-dibenzo(a,d)cyclohepten-5-ol 5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol 5-(3-(DiMethylaMino)propyl)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ol 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ol 5H-Dibenzo(a,d)cyclohepten-5-ol, 10,11-dihydro-5-(3-dimethylaminopropyl)- 5H-Dibenzo[a,d]cyclohepten-5-ol,5-[3-(dimethylamino)propyl]-10,11-dihydro- 5H-Dibenzo(a,d)cyclohepten-5-ol, 5-(3-(dimethylamino)propyl)-10,11-dihydro- Amitriptyline Related Compound B (25 mg) (5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-ol)
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CAS | 1159-03-1
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EINECS | 214-594-6 |
InChI | InChI=1/C20H25NO/c1-21(2)15-7-14-20(22)18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)20/h3-6,8-11,22H,7,12-15H2,1-2H3 |
5H-Dibenzo(a,d)cyclohepten-5-ol, 10,11-dihydro-5-(3-dimethylaminopropyl)- - Physico-chemical Properties
Molecular Formula | C20H25NO
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Molar Mass | 295.42 |
Density | 1.079±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 119-120℃ |
Boling Point | 413.0±40.0 °C(Predicted) |
Flash Point | 186.4°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 1.46E-07mmHg at 25°C |
Appearance | Solid |
Color | Off-White to Beige |
pKa | 13.52±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.583 |
5H-Dibenzo(a,d)cyclohepten-5-ol, 10,11-dihydro-5-(3-dimethylaminopropyl)- - Risk and Safety
5H-Dibenzo(a,d)cyclohepten-5-ol, 10,11-dihydro-5-(3-dimethylaminopropyl)- - Introduction
5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo [A,D] cyclohepten-5-ol, also known as geraniol. The following is information about the properties, uses, preparation and safety of geraniol:
Nature:
-Geraniol is an organic compound with a chemical formula of C15H25NO and a relative molecular mass of 235.37g/mol.
-It is a colorless to pale yellow liquid with a pine-like fragrance.
-Geraniol is soluble in ethanol, chloroform and benzene solvents, insoluble in water.
Use:
-geraniol is often used as an ingredient in spices and flavors to give products a cedar aroma.
-It is also commonly used as a fragrance additive in cosmetics, personal care products, detergents, etc.
-Geraniol also has certain antibacterial and bactericidal effects, and has certain applications in the field of medicine.
Method:
-The preparation of geraniol can be obtained by reacting 1,4-cycloheptadiene and 3-dimethylaminopropanol to produce a nucleophilic addition reaction.
-The reaction conditions often need to be carried out under an inert atmosphere at a low temperature, and the reaction yield can be improved by accurately controlling the reaction conditions.
Safety Information:
-geraniol may have an irritating effect on the skin and eyes at a certain concentration, and personal protective measures should be paid attention to when using it.
-When in contact with skin, wash immediately with water and soap.
-Avoid inhaling or swallowing. If inhaled or ingested, seek medical attention immediately.
-When using geraniol, follow safe operating procedures and avoid contact with oxidizing agents.
-geraniol should be stored in a cool, dry, well-ventilated place, away from open flames and high temperatures.
Last Update:2024-04-09 19:05:45